Emergency myelopoiesis distinguishes multisystem inflammatory syndrome in children from pediatric severe COVID-19.

Katerina Roznik Temesgen E AndargieT Scott JohnstonOren GordonYi WangNadine Peart Akindele Deborah Persaud Annukka A R Antar Yukari C ManabeWeiqiang ZhouHongkai Ji Sean Agbor-Enoh Andrew H KarabaElizabeth A ThompsonAndrea L Cox

Published in: The Journal of infectious diseases (2024)

Immune cell signatures of EM combined with elevated innate immune cell-derived cfDNA levels distinguish MIS-C from SAC in children and provide mechanistic insight into dysregulated immunity contributing towards MIS-C, offering potential diagnostic and therapeutic targets.

Keyphrases

innate immune
young adults
coronavirus disease
sars cov
emergency department
public health
healthcare
oxidative stress
early onset
case report
genome wide
dna methylation
gene expression
risk assessment
climate change
human health
respiratory syndrome coronavirus