Effects of a Catechol-Functionalized Hyaluronic Acid Patch Combined with Human Adipose-Derived Stem Cells in Diabetic Wound Healing.

Chang Sik PakChan Young HeoJisoo ShinSoo Young MoonSeung-Woo ChoHyo Jin Kang

Published in: International journal of molecular sciences (2021)

The combination of HA-CA and ADSCs provided synergistic wound healing effects by maximizing paracrine signaling and angiogenesis via the PI3K/AKT pathway. Therefore, ADSC-loaded HA-CA might represent a novel strategy for the treatment of DBW.

Keyphrases

wound healing
hyaluronic acid
endothelial cells
protein kinase
induced pluripotent stem cells
quantum dots
type diabetes
drug delivery
pluripotent stem cells
combination therapy