Carbonic anhydrases III and IX are new players in the crosstalk between adrenocortical carcinoma and its altered adipose microenvironment.

L FeiG CantiniA NocentiniP NardiniS CatarinicchiaL CanuT ErcolinoG QuartararoG NesiM GacciM MaggiC HantelM MannelliC T SupuranMichaela Luconi

Published in: Journal of endocrinological investigation (2023)

Our findings highlight a modulation of CAIII and CAIX in the metabolic crosstalk between ACC and its local adipose microenvironment, suggesting that CAs might represent a potential target for novel anticancer therapies.

Keyphrases

stem cells
adipose tissue
insulin resistance
crispr cas
genome editing
skeletal muscle
climate change