Resveratrol, Epigallocatechin Gallate and Curcumin for Cancer Therapy: Challenges from Their Pro-Apoptotic Properties.
Adele ChimentoMaria D'AmicoArianna De LucaFrancesca Luisa ConfortiVincenzo PezziFrancesca De AmicisPublished in: Life (Basel, Switzerland) (2023)
Plant-derived bioactive compounds are gaining wide attention for their multiple health-promoting activities and in particular for their anti-cancer properties. Several studies have highlighted how they can prevent cancer initiation and progression, improve the effectiveness of chemotherapy, and, in some cases, limit some of the side effects of chemotherapy agents. In this paper, we provide an update of the literature on the anti-cancer effects of three extensively studied plant-derived compounds, namely resveratrol, epigallocatechin gallate, and curcumin, with a special focus on the anti-cancer molecular mechanisms inducing apoptosis in the major types of cancers globally.
Keyphrases
- cancer therapy
- cell death
- systematic review
- locally advanced
- healthcare
- public health
- papillary thyroid
- randomized controlled trial
- anti inflammatory
- oxidative stress
- drug delivery
- endoplasmic reticulum stress
- mental health
- working memory
- multidrug resistant
- cell cycle arrest
- health information
- squamous cell carcinoma
- radiation therapy
- childhood cancer
- chemotherapy induced
- rectal cancer
- cell proliferation
- case control
- lymph node metastasis
- solid state
- health promotion