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Novel time-synchronized immune-guided partial tumor irradiation: Proof of principle trial.

S TubinM L AshdownM M AhmedC GuhaG SalernoB CeledinB TrummerS DemscharW Raunik
Published in: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (2024)
This study highlights the profound impact PTI can have on a highly palliative patient cohort previously deemed beyond therapeutic hope. With 41 % of these patients still alive after a median follow-up of 50 months, PTI offers a potential lifeline for those facing advanced, treatment-resistant cancers. This approach generated also distant immunogenic anti-tumor responses, offering a promising new avenue for the treatment of advanced cancers.
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