Expression of nerve growth factor carried by pseudotyped lentivirus improves neuron survival and cognitive functional recovery of post-ischemia in rats.
Jia-Yu CaoYong LinYan-Fei HanSheng-Hao DingYi-Ling FanYao-Hua PanBing ZhaoQin-Hua GuoWen-Hua SunJie-Qing WanXiao-Ping TongPublished in: CNS neuroscience & therapeutics (2018)
This study demonstrates a potential β-NGF gene therapy by utilization of pseudolentivirus in ischemia and indicates future applications of NGF gene treatment in ischemic patients.
Keyphrases
- growth factor
- gene therapy
- end stage renal disease
- chronic kidney disease
- ejection fraction
- newly diagnosed
- poor prognosis
- prognostic factors
- peritoneal dialysis
- gene expression
- climate change
- dna methylation
- patient reported outcomes
- risk assessment
- transcription factor
- combination therapy
- genome wide identification