Characterization of pharmaceutic structured triacylglycerols by high-performance liquid chromatography/tandem high-resolution mass spectrometry and its application to structured fat emulsion injection.
Hao ZhengRui YangZhe WangJue WangJin-Lan ZhangHuimin SunPublished in: Rapid communications in mass spectrometry : RCM (2020)
This study has provided a rapid and accurate approach for the identification and quality control of pharmaceutic STAGs and structured fat emulsion injection and this approach can be extended to other lipid pharmaceutic excipients and used as an effective and reasonable control to guarantee the quality of pharmaceutical preparations.
Keyphrases
- high performance liquid chromatography
- quality control
- high resolution mass spectrometry
- tandem mass spectrometry
- liquid chromatography
- ultra high performance liquid chromatography
- mass spectrometry
- adipose tissue
- simultaneous determination
- gas chromatography
- fatty acid
- solid phase extraction
- ultrasound guided
- high resolution
- quality improvement
- quantum dots