Effectiveness of Bio-K+ for the prevention of Clostridioides difficile infection: Stepped-wedge cluster-randomized controlled trial.
Jenine R LealYe ShenPeter FarisBruce DaltonDeana SabudaWrechelle OcampoLauren C BreseeBlanda ChowJared R FletcherElizabeth HendersonJaime KaufmanJoseph KimMaitreyi RamanScott KraftNicole C LamontOscar LariosBayan MissaghiJayna Holroyd-LeducThomas LouieJohn M ConlyPublished in: Infection control and hospital epidemiology (2023)
Hospitals considering probiotics as a primary prevention strategy should consider the baseline incidence of HA-CDI in their population and timing of probiotics relative to the start of antimicrobial administration.