Feasibility and metabolic outcomes of a well-formulated ketogenic diet as an adjuvant therapeutic intervention for women with stage IV metastatic breast cancer: The Keto-CARE trial.
Alex BugaDavid G HarperTeryn N SapperParker N HydeBrandon FellRyan DickersonJusten T StonerMadison L KackleyChristopher D CrabtreeDrew D DeckerBradley T RobinsonGerald KrystalKatherine BinzelMaryam B LustbergJeff S VolekPublished in: PloS one (2024)
Women diagnosed with MBC undergoing chemotherapy can safely achieve and maintain nutritional ketosis, while improving body composition and insulin resistance, out to six months.
Keyphrases
- body composition
- metastatic breast cancer
- polycystic ovary syndrome
- insulin resistance
- resistance training
- randomized controlled trial
- bone mineral density
- healthcare
- study protocol
- early stage
- palliative care
- adipose tissue
- phase iii
- physical activity
- metabolic syndrome
- high fat diet
- clinical trial
- quality improvement
- weight loss
- type diabetes
- phase ii
- locally advanced
- skeletal muscle
- pregnancy outcomes
- pain management
- glycemic control
- squamous cell carcinoma
- breast cancer risk
- open label
- radiation therapy
- rectal cancer