Genetic and antiretroviral drug resistance mutations analysis of reverse transcriptase and protease gene from Pakistani people living with HIV-1.

Dilsha SiddiquiUzma BadarMahnoor JavaidNida FarooquiSharaf Ali ShahAyesha IftikharFaisal SultanFatima MirSofia FurqanSyed Faisal MahmoodSyed Hani Abidi

Published in: PloS one (2023)

High prevalence of DRMs, especially against previous first-line treatment in ART- naïve and the accumulation of DRMs in ART-experienced groups is concerning and warrants that a more extensive DRM survey be carried out to inform first-line and second-line ART regimen recommendations.

Keyphrases

hiv infected
antiretroviral therapy
genome wide
human immunodeficiency virus
copy number
hiv aids
hiv infected patients
cross sectional
clinical practice
gene expression
genome wide identification