Comparative assessment of proliferation and immunomodulatory potential of Hypericum perforatum plant and callus extracts on mesenchymal stem cells derived adipose tissue from multiple sclerosis patients.
Negin AfsharzadehFahimeh Lavi ArabMojtaba SankianLeila SamieiNafiseh Sadat TabasiDanial AfsharzadehKarim NikkhahMahmoud MahmoudiPublished in: Inflammopharmacology (2021)
High concentrations of HP extracts showed effectiveness on AT-MSCs proliferation and immunomodulatory properties with a certain consequence in callus extract. HP extracts may be considered as supplementary treatments for the patients who receiving MSCs transplantation.
Keyphrases
- mesenchymal stem cells
- multiple sclerosis
- adipose tissue
- umbilical cord
- end stage renal disease
- signaling pathway
- ejection fraction
- newly diagnosed
- systematic review
- peritoneal dialysis
- randomized controlled trial
- cell therapy
- bone marrow
- oxidative stress
- prognostic factors
- stem cells
- high fat diet
- insulin resistance
- metabolic syndrome
- type diabetes
- patient reported outcomes
- skeletal muscle
- risk assessment
- anti inflammatory
- cell wall