Login / Signup

White matter and latency of visual evoked potentials during maturation: A miniature pig model of adolescent development.

Peter KochunovL Elliot HongAnn SummerfeltSi GaoP Leon BrownMatthew TerziAshley AchesonMarty G WoldorffEls FieremansAli AbdollahzadehKorrapati V SathyasaikumarSarah M ClarkRobert SchwarczPaul D ShepardGreg I Elmer
Published in: Journal of neuroscience methods (2024)
Good agreement between reduction in the latency of fVEPs and maturation of cerebral WM was interpreted as evidence for ongoing myelination and confirmation of the minipig as a viable research platform. Adolescent development in minipigs can be studied using human neuroimaging and neurophysiological protocols and followed up with more invasive assays to investigate key neurodevelopmental hypotheses in psychiatry.
Keyphrases
  • white matter
  • young adults
  • mental health
  • endothelial cells
  • high throughput
  • multiple sclerosis
  • induced pluripotent stem cells
  • brain injury
  • pluripotent stem cells
  • cerebral ischemia
  • congenital heart disease