Mucin expression in gastric- and gastro-oesophageal signet-ring cell cancer: results from a comprehensive literature review and a large cohort study of Caucasian and Asian gastric cancer.

K G P KerckhoffsD H W LiuL SaragoniR S van der PostR LangerM BencivengaM IglesiasG GalloL C HewittG E FazziA M VosF RenaudT YoshikawaT OshimaA TomezzoliG de ManzoniTomio AraiR KushimaF CarneiroHeike I Grabsch

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2020)

This is the first study to suggest that mucin stains do not help to differentiate between SRC-GC and non-SRC-GC. However, mucin stains appear to be able to identify GC patients with different outcome. To our surprise, the relationship between outcome and mucin expression seems to differ between Caucasian and Asian GC patients which warrants further investigations.

Keyphrases

poor prognosis
gas chromatography
tyrosine kinase
newly diagnosed
ejection fraction
single cell
african american
cell therapy
long non coding rna
case report
squamous cell carcinoma
stem cells
patient reported outcomes
chronic kidney disease
squamous cell
tandem mass spectrometry
high resolution
patient reported