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[Molecular mimicry between human thyroid peroxidase, thyroglobulin, cosinophil peroxidase, IL-24 and microorganisms antigens].

Andrés SánchezValentina GarcíaYuliana Marcela Emiliani-NavarroJorge SánchezJuan Camilo Ramos-GomezSonia Karina González-RangelMarlon Munera-Gomez
Published in: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) (2024)
TPO and EPX antigens shared potential cross-reactive epitopes with bacterial and nematode proteins, suggesting that molecular mimicry could be a mechanism that explains the relationship between infections and urticaria/hypothyroidism. In vitro work is needed to demonstrate the results obtained in the in silico analysis.
Keyphrases
  • hydrogen peroxide
  • endothelial cells
  • dendritic cells
  • single molecule
  • molecular docking
  • induced pluripotent stem cells
  • pluripotent stem cells
  • immune response
  • fine needle aspiration
  • molecular dynamics simulations