Types of deviation and review criteria in pretreatment central quality control of tumor bed boost in medulloblastoma-an analysis of the German Radiotherapy Quality Control Panel in the SIOP PNET5 MB trial.
Stefan DietzschAnnett BraesigkClemens SeidelJulia RemmeleRalf KitzingTina SchlenderMartin MynarekDirk GeismarKarolina JablonskaRudolf SchwarzMontserrat PazosDamien C WeberSilke FrickKristin GurtnerChristiane MatuschekSemi Ben HarrabiAlbrecht GlückVictor LewitzkiKarin DieckmannMartin BeneschNicolas U GerberDenise ObrechtStefan RutkowskiBeate TimmermannRolf-Dieter KortmannPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2021)
In this analysis of pretreatment RT-QC, protocol deviations were present in a high proportion of initial TB plan proposals. These findings emphasize the importance of pretreatment RT-QC in clinical trials for MB. Based on these data, a proposal for RT-QC criteria for tumor bed boost in non-metastatic MB was developed.