Sex-related differences of fatty acid-binding protein 4 and leptin levels in atrial fibrillation.
J N López-CanoaM Couselo-SeijasA BalujaL González-MelchorA RozadosV Llorente-CortésD de Gonzalo-CalvoJ M GuerraD ViladesR LetaJ L Martínez-SandeF J García-SearaMoises Rodriguez-MañeroJ R González-JuanateyS EirasM Rodríguez-MañeroPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2021)
The major finding of the present study is the sex-based differences of FABP4 and leptin levels according to AF burden. These adipokines are associated with oxidative stress, inflammatory and autonomic indirect markers, indicating that they may play a role in AF perpetuation.
Keyphrases
- atrial fibrillation
- binding protein
- oxidative stress
- fatty acid
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- heart failure
- direct oral anticoagulants
- heart rate variability
- dna damage
- percutaneous coronary intervention
- risk factors
- ischemia reperfusion injury
- blood pressure
- signaling pathway
- acute coronary syndrome