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Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting.

Christoph GruberLea KrautnerValter BergantVincent GrassZhe MaLara RheinemannAriane KrusFriederike ReinhardtLyupka MazneykovaMarianne Rocha-HaslerDong-Jiunn Jeffery TruongGil Gregor WestmeyerAndreas PichlmairGregor EbertFlorian GiesertWolfgang Wurst
Published in: Cell discovery (2024)
Keyphrases
  • highly efficient
  • crispr cas
  • genome editing
  • cancer therapy
  • nucleic acid
  • drug delivery