Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury by Regulating the NF-κB/NLRP3 Signaling Pathway.
Yun-Liang TangXiaoyang DongGengfa ChenWen YeJunwei KangYang TangZhen FengPublished in: Neurorehabilitation and neural repair (2020)
Taken together, the present study indicates that VNS may attenuate brain damage after TBI by inhibiting oxidative stress, inflammation, and apoptosis, possibly through the NF-κB/NLRP3 signaling pathway.
Keyphrases
- signaling pathway
- oxidative stress
- traumatic brain injury
- pi k akt
- induced apoptosis
- epithelial mesenchymal transition
- diabetic rats
- cell cycle arrest
- ischemia reperfusion injury
- dna damage
- nlrp inflammasome
- white matter
- severe traumatic brain injury
- cell proliferation
- multiple sclerosis
- endoplasmic reticulum stress
- immune response
- mild traumatic brain injury
- toll like receptor
- subarachnoid hemorrhage