Blood Pressure Response to Losartan and Continuous Positive Airway Pressure in Hypertension and Obstructive Sleep Apnea.
Erik ThunströmKarin ManhemAnnika RosengrenYüksel PekerPublished in: American journal of respiratory and critical care medicine (2016)
Losartan reduced BP in OSA, but the reductions were less than in no-OSA. Add-on CPAP therapy resulted in no significant changes in 24-hour BP measures except in patients using CPAP efficiently. Clinical trial registered with www.clinicaltrials.gov (NCT00701428).
Keyphrases
- obstructive sleep apnea
- positive airway pressure
- blood pressure
- sleep apnea
- clinical trial
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- angiotensin ii
- heart rate
- prognostic factors
- randomized controlled trial
- study protocol
- peritoneal dialysis
- mesenchymal stem cells
- blood glucose
- skeletal muscle
- patient reported
- weight loss
- glycemic control