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Myopia progression after cessation of low-dose atropine eyedrops treatment: A two-year randomized, double-masked, placebo-controlled, cross-over trial.

Shifei WeiShi-Ming LiWenzai AnJialing DuXintong LiangYunyun SunJiahe GanWeiling BaiJiaxin TianZhining CaiLei YinNing Li Wang
Published in: Acta ophthalmologica (2022)
The difference in myopia progression between atropine-placebo group and placebo-atropine group in Phase 1 was similar to Phase 2 during the cross-over treatment. Through our cross-over trial, the results suggest that there is no rebound effect after using 0.01% atropine eye drops to prevent progression of myopia.
Keyphrases
  • phase iii
  • placebo controlled
  • double blind
  • phase ii
  • low dose
  • clinical trial
  • open label
  • study protocol
  • randomized controlled trial
  • high dose
  • squamous cell carcinoma
  • optical coherence tomography
  • locally advanced