INTRAPERITONEAL CHEMOTHERAPY FOR GASTRIC CANCER WITH PERITONEAL CARCINOMATOSIS: STUDY PROTOCOL OF A PHASE II TRIAL.

Marcus Fernando Kodama Pertille Ramos Marina Alessandra Pereira Amir Zeide Charruf Carolina Ribeiro Victor João Vitor Antunes Marques Gregorio Luciana Bastos Valente Alban Camila Motta Venchiarutti Moniz Bruno Zilberstein Evandro Sobroza de Mello Paulo Marcelo Gehm Hoff Ulysses Ribeiro Junior Andre Roncon Dias

Published in: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery (2023)

Therapies for advanced gastric cancer patients have been evaluated in clinical trials but without success in patients with peritoneal metastasis. The treatment proposed in this trial can be promising, with easy catheter implantation and ambulatory intraperitoneal chemotherapy regime. Verifying the efficacy and safety of paclitaxel with systemic chemotherapy is an important progress that this study intends to investigate.

Keyphrases

clinical trial
study protocol
locally advanced
randomized controlled trial
open label
chemotherapy induced
phase iii
blood pressure
phase ii
rectal cancer
radiation therapy
combination therapy
double blind
drug induced