Honey bee (Apis mellifera) larval pheromones may regulate gene expression related to foraging task specialization.

Our results suggest that, as social signals, pheromones alter expression patterns of foraging-related genes in the bee's brain to increase pollen foraging at both long and short time scales. These results provide new insights into how social signals and task specialization are potentially integrated at the molecular level, and highlights the possible role that brain gene expression may play in honey bee behavioral plasticity across time scales.