Elevated expression of B7 homolog 4 is associated with disease progression in upper urinary tract urothelial carcinoma.
Tomoya MizunoTakao KamaiToyonori TsuzukiDaisaku NishiharaToshiki KijimaKyoko AraiKen-Ichiro YoshidaPublished in: Cancer immunology, immunotherapy : CII (2021)
These findings suggest that B7-H4 expression in the tumor microenvironment influences the progression of UTUC through cancer immunity and metabolic activity. Tumor cell-associated B7-H4 might be a potential target for cancer immunotherapies.