High YKL-40 serum levels and its expression in the muscle tissues of patients with antisynthetase syndrome.

Renata Casseb de Souza CarboniGustavo Luiz Behrens PintoSamuel Katsuyuki Shinjo

Published in: Advances in rheumatology (London, England) (2021)

High YKL-40 serum levels were observed in patients with ASSD and correlated positively with TNF-α serum levels. Moreover, YKL-40 was expressed by the inflammatory cells of the muscle tissue.

Keyphrases

skeletal muscle
induced apoptosis
poor prognosis
rheumatoid arthritis
gene expression
cell cycle arrest
oxidative stress
case report
long non coding rna
cell proliferation
pi k akt