TAZ maintains telomere length in TNBC cells by mediating Rad51C expression.

Lu YangBo WangXinyan JiaoCan ZhouSu ChenXiaoqian GaoWei SunShaoran SongJuan LiJie LiuYaochun WangPei-Jun Liu

Published in: Breast cancer research : BCR (2021)

This study supports the notion that TAZ is an oncogenic factor in TNBC, and further reveals a novel telomere-related pathway that is employed by TAZ to regulate TNBC.

Keyphrases

induced apoptosis
poor prognosis
cell cycle arrest
dna repair
transcription factor
oxidative stress
signaling pathway
binding protein
endoplasmic reticulum stress
drug induced