A case of tamoxifen-induced hypertriglyceridemia monitoring the changes in lipoprotein fractions over time.
Hayato IsobeMasashi ShimodaYuki KanFuminori TatsumiYukino KatakuraTomohiko KimuraAtsushi ObataKenji KoharaShuhei NakanishiTomoatsu MuneKohei KakuHideaki KanetoPublished in: BMC endocrine disorders (2021)
From these results, we confirmed that tamoxifen certainly changes lipoprotein metabolism through suppression of post-heparin lipolytic activity. It is very important to evaluate the balance between benefit and risk before dosing tamoxifen and survey lipid profiles constantly during treatment to avoid life-threatening complication when prescription of tamoxifen is planned.