Cytokine Responses during Mycobacterium tuberculosis H37Rv and Ascaris lumbricoides Costimulation Using Human THP-1 and Jurkat Cells, and a Pilot Human Tuberculosis and Helminth Coinfection Study.
Khethiwe Nomcebo BhenguRavesh SinghPragalathan NaidooMiranda N Mpaka-MbathaNomzamo Nembe-MafaZilungile Lynette Mkhize-KwitshanaPublished in: Microorganisms (2023)
Data suggest that helminths induce a predominant Th2/Treg response which may downregulate critical Th1 responses that are crucial for tuberculosis protection.
Keyphrases
- mycobacterium tuberculosis
- endothelial cells
- pulmonary tuberculosis
- induced pluripotent stem cells
- induced apoptosis
- pluripotent stem cells
- emergency department
- clinical trial
- oxidative stress
- machine learning
- big data
- cell proliferation
- hepatitis c virus
- human immunodeficiency virus
- adverse drug
- data analysis
- cell death
- hiv infected