Spot urinary sodium guided titration of intravenous diuretic therapy in acute heart failure: A pilot randomised controlled trial.
Maryam Khorramshahi BayatWandy ChanKaren HayScott McKenziePolash AdhikariGavin FincherFaye JordanIsuru RanasinghePublished in: European heart journal. Quality of care & clinical outcomes (2024)
UNa-guided titration of diuretic therapy in AHF is feasible and safer than titration based on clinical signs and symptoms of congestion, with more effective decongestion at 48 hours. Further large-scale trials are needed to determine if the superiority of this approach translates into improved patient outcomes.