Significant association between admission serum monocyte chemoattractant protein-1 and early changes in myocardial function in patients with first ST-segment elevation myocardial infarction after primary percutaneous coronary intervention.
Yong ZhuChengping HuYu DuJianwei ZhangJinxing LiuHongya HanYing-Xin ZhaoPublished in: BMC cardiovascular disorders (2019)
MCP-1 upon admission not only correlated positively with hs-cTnI at different time points and peak hs-cTnI, but also associated inversely with early improvements in myocardial function in patients with first STEMI. So we speculated that suppression the expression of MCP-1 via various ways may be a promising therapeutic target in myocardial I/R injury in the future.
Keyphrases
- st segment elevation myocardial infarction
- percutaneous coronary intervention
- st elevation myocardial infarction
- left ventricular
- acute coronary syndrome
- acute myocardial infarction
- coronary artery disease
- antiplatelet therapy
- coronary artery bypass grafting
- emergency department
- poor prognosis
- binding protein
- coronary artery bypass
- atrial fibrillation
- dendritic cells
- heart failure
- amino acid