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The human embryo selection arena is associated with transposable element activity.

Anna OsnatoVincent PasqueLaurent David
Published in: PLoS biology (2023)
Our current understanding of early human development is limited. A study in PLOS Biology found a previously undefined group of cells that diverges from the main lineages and undergo apoptosis through the activity of young transposable elements.
Keyphrases
  • endothelial cells
  • cell cycle arrest
  • induced apoptosis
  • oxidative stress
  • cell death
  • induced pluripotent stem cells
  • pluripotent stem cells
  • endoplasmic reticulum stress
  • pi k akt
  • signaling pathway