Dysregulation of COVID-19 related gene expression in the COPD lung.

Alastair WatsonLisa ÖbergBastian AngermannC Mirella SpallutoMichael HühnHannah BurkeDoriana CelluraAnna FreemanDaniel MuthasDamla EtalGraham BelfieldFredrik KarlssonKarl NordströmKris OstridgeKarl J StaplesAlastair Watsonnull null

Published in: Respiratory research (2021)

This study identifies key differences in expression of genes related to susceptibility and aetiology of COVID-19 within the COPD lung. Further studies to understand the impact on clinical course of disease are now required.

Keyphrases

coronavirus disease
gene expression
sars cov
chronic obstructive pulmonary disease
genome wide
lung function
poor prognosis
dna methylation
respiratory syndrome coronavirus
transcription factor
air pollution