Amelogenesis imperfecta: A novel FAM83H mutation and characteristics of periodontal ligament cells.

Nunthawan NowwaroteThanakorn TheerapanonThanaphum OsathanonPrasit Pavasant Thantrira PorntaveetusVorasuk Shotelersuk

Published in: Oral diseases (2018)

We identified the novel mutation in FAM83H associated with autosomal dominant hypocalcified AI. The FAM83H cells showed reduced cell proliferation and expression of osteogenic markers, suggesting altered PDLCs in FAM83H-associated AI.

Keyphrases

induced apoptosis
cell proliferation
cell cycle arrest
artificial intelligence
poor prognosis
mesenchymal stem cells
signaling pathway
oxidative stress
bone marrow
pi k akt
cell death