Neurogenic tumours of the posterior mediastinum and differential diagnosis considerations.
Michael A den BakkerAnnikka WeissferdtPublished in: Histopathology (2023)
The mediastinal compartment harbours vital organs and structures, including the heart, great vessels, major airways, and thymus. These structures are embedded in and associated with soft-tissue elements consisting of adipose and fibro-collagenous tissue in which soft-tissue tumours may develop. A detailed inventory of soft-tissue tumours that may be encountered in the mediastinum based on the WHO 2013 classification was published in 2015. In addition, several comprehensive reviews on mediastinal soft-tissue pathology are available, including reviews focusing specifically on a single tumour type. This review will focus on primary neurogenic and spindle cell tumours of the somatic soft tissue of the posterior mediastinum and provide a discussion of the pertinent differential diagnoses.
Keyphrases
- soft tissue
- lymph node
- spinal cord injury
- high resolution
- machine learning
- heart failure
- cystic fibrosis
- deep learning
- systematic review
- randomized controlled trial
- stem cells
- gene expression
- adipose tissue
- metabolic syndrome
- cell therapy
- atrial fibrillation
- bone marrow
- insulin resistance
- mesenchymal stem cells
- genome wide