Intranasal Midazolam versus Rectal Diazepam for the Management of Canine Status Epilepticus: A Multicenter Randomized Parallel-Group Clinical Trial.

Marios CharalambousS F M BhattiL Van HamS PlattN D JefferyA TipoldJohannes S SiedenburgH A VolkD HasegawaA GallucciG GandiniM MusteataE IvesA E Vanhaesebrouck

Published in: Journal of veterinary internal medicine (2017)

IN-MDZ is a quick, safe and effective first-line medication for controlling status epilepticus in dogs and appears superior to R-DZP. IN-MDZ might be a valuable treatment option when intravenous access is not available and for treatment of status epilepticus in dogs at home.

Keyphrases

clinical trial
double blind
open label
healthcare
randomized controlled trial
phase ii
high dose
combination therapy
adverse drug
drug induced