Glucose metabolic upregulation via phosphorylation of S6 ribosomal protein affects tumor progression in distal cholangiocarcinoma.

Atsuro FujinagaTeijiro HirashitaYuka HirashitaKumiko SakaiMasahiro KawamuraTakashi MasudaYuichi EndoMasayuki OhtaKazunari MurakamiMasafumi Inomata

Published in: BMC gastroenterology (2023)

Upregulation of glucose metabolism via phosphorylation of S6 ribosomal protein appeared to play a role in tumor progression in dCCA. mTORC1 may be a therapeutic target for dCCA.

Keyphrases

poor prognosis
long non coding rna
cell proliferation
protein protein
amino acid
protein kinase
signaling pathway
binding protein
blood glucose
blood pressure
small molecule
adipose tissue
metabolic syndrome
insulin resistance