Does central sensitization affect hyperalgesia after staged bilateral total knee arthroplasty? A randomized controlled trial.

Hyun Jung KohYong InEun Sung KimJae Woong HwangJi Yeong KimSoo Jin LimHue Jung Park

Published in: The Journal of international medical research (2021)

We could not confirm that hyperalgesia was only related to central sensitization with low-dose ketamine. Other factors might be also associated with the hyperexcitability of nociceptive stimuli.Clinical Research Information Service (CRIS) trial registry no: KCT0001481.

Keyphrases

neuropathic pain
total knee arthroplasty
low dose
spinal cord
mental health
healthcare
total hip
spinal cord injury
study protocol
high dose
pain management
case report
randomized controlled trial