DNA Copy Number Aberrations and Expression of ABC Transporter Genes in Breast Tumour: Correlation with the Effect of Neoadjuvant Chemotherapy and Prognosis of the Disease.
Matvey M TsyganovMarina K IbragimovaKseniya A GaptulbarovaIrina A TsydenovaDaria S DolgashevaEvgeniy Y GarbukovAnastasia A FrolovaElena M SlonimskayaNikolai V LitvyakovPublished in: Pharmaceutics (2022)
The study showed that the aberrant state of ABC transporter genes, as well as a decrease in the expression of these genes, is a predictor of the effectiveness of therapeutic treatment and a potential prognostic marker of metastatic survival.
Keyphrases
- copy number
- genome wide
- neoadjuvant chemotherapy
- mitochondrial dna
- poor prognosis
- dna methylation
- bioinformatics analysis
- genome wide identification
- lymph node
- locally advanced
- small cell lung cancer
- squamous cell carcinoma
- systematic review
- sentinel lymph node
- circulating tumor
- gene expression
- binding protein
- genome wide analysis
- risk assessment
- climate change
- circulating tumor cells