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Epidemiology of interstitial lung disease in patients with metastatic breast cancer at baseline and after treatment with HER2-directed therapy: a real-world data analysis.

Jeanna Wallenta LawAlicyn CampbellColin WellerColden JohansonRonda BroomeElisabeth PiaultMonika A IzanoAndrew SchragMary TranThomas D BrownHenry G Kaplan
Published in: Breast cancer research and treatment (2022)
This real-world population of patients with mBC had a high prevalence of ILD prior to HER2-directed therapy, reflecting the multifactorial causation of interstitial lung changes. The cumulative incidence of ILD in patients receiving HER2-directed therapy for mBC augments prior reports. Symptomatic presentation suggests an opportunity for early intervention.
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