Is Impregnation of Xenograft with Caffeine Effective on Bone Healing Rate in Mandibular Defects? A Pilot Histological Animal Study.

Sahand SamieiradVajiheh MianbandiHamideh Salari SedighMajid Hosseini-AbrishamiFarid ShiezadehHossein BagheriElahe TohidiNasrollah Saghravanian

Published in: Journal of maxillofacial and oral surgery (2019)

This study suggested that the application of 1.5% caffeinated Bio-Oss in bone defects of dogs resulted in the higher new bone formation. However, further clinical trials are needed to support its relevancy.

Keyphrases

clinical trial
bone mineral density
randomized controlled trial
postmenopausal women
open label
bone loss