Pyometra alters the redox status and expression of estrogen and progesterone receptors in the uterus of domestic cats.
Acácia Eduarda de Jesus NascimentoLuciano Cardoso SantosBianca Reis SantosEmilly Oliveira SantosMaria Clara da Silva Galrão CunhaPaola Pereira das Neves SnoeckMário Sérgio Lima de LavorJuneo Freitas SilvaPublished in: Journal of feline medicine and surgery (2023)
The findings of this study showed that pyometra is associated with oxidative stress in the uterus of domestic cats and alterations of the profile of sex steroid receptors, especially ERα and PR, and of antioxidant enzymes, suggesting that changes in these mediators may play a role with the etiopathogenesis of this disease.