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Cathepsin D regulates lipid metabolism in murine steatohepatitis.

Tom HoubenYvonne OligschlaegerTim HendrikxAlbert V BitorinaSofie M A WalenberghPatrick J van GorpMarion J J GijbelsSilvia FriedrichsJogchum PlatFrank G SchaapDieter LütjohannMarten H HofkerRonit Shiri-Sverdlov
Published in: Scientific reports (2017)
CTSD is a key player in the development of hepatic inflammation and dyslipidemia. Therefore, aiming at the inhibition of the activity of CTSD may lead to novel treatments to combat NASH.
Keyphrases
  • oxidative stress
  • fatty acid