Changes in OCT4 expression play a crucial role in the lineage specification and proliferation of preimplantation porcine blastocysts.
Mingyun LeeJong-Nam OhGyung Cheol ChoeSeung-Hun KimKwang-Hwan ChoiDong-Kyung LeeJinsol JeongChang-Kyu LeePublished in: Cell proliferation (2022)
Taken together, our results demonstrated that OCT4 leads pluripotency in porcine blastocysts and also plays an important role in ICM formation, secondary cell fate decision, and cell proliferation.