Berberine regulates bone metabolism in apical periodontitis by remodelling the extracellular matrix.
Yujia CuiJing XieLinyi CaiDemao ZhangJianxun SunXuedong ZhouPublished in: Oral diseases (2021)
Berberine controlled the inflammatory response and regulated bone metabolism in AP by reducing metalloproteinase expression and increasing lysyl oxidases expression.