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PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

Cédric WalkerTasneem TalawallaRobert TothAkhil AmbekarKien ReaOswin ChamianFan FanSabina BerezowskaSven RottenbergAnant MadabhushiMarie MaillardLaura BarisoniHugo Mark HorlingsAndrew Janowczyk
Published in: NPJ digital medicine (2024)
The discovery of patterns associated with diagnosis, prognosis, and therapy response in digital pathology images often requires intractable labeling of large quantities of histological objects. Here we release an open-source labeling tool, PatchSorter, which integrates deep learning with an intuitive web interface. Using >100,000 objects, we demonstrate a >7x improvement in labels per second over unaided labeling, with minimal impact on labeling accuracy, thus enabling high-throughput labeling of large datasets.
Keyphrases
  • high throughput
  • deep learning
  • convolutional neural network
  • machine learning
  • small molecule
  • single cell
  • stem cells
  • bone marrow
  • mesenchymal stem cells
  • smoking cessation