Serum Neuropeptide Y Levels Are Associated with TNF-α Levels and Disease Activity in Rheumatoid Arthritis.
Melissa Ramirez-VillafañaAna Miriam Saldaña-CruzJavier Alejandro Aceves-AcevesEdsaul Emilio Perez GuerreroNicte S Fajardo-RobledoEdy David Rubio ArellanoCesar Arturo Nava-ValdiviaMaria O Carrillo-EscalanteSylvia Elena Totsuka-SuttoDavid Cardona-MüllerBetsabe Contreras-HaroMario Salazar-PáramoErnesto German Cardona MuñozMiguel HuertaJorge Ivan Gamez-NavaNorma Alejandra Rodriguez-JimenezLaura Gonzalez LopezPublished in: Journal of immunology research (2020)
Higher NPY levels are an independent marker of disease activity in RA. This study encourages the quantification of NPY levels as a surrogate marker for RA-active. Future studies evaluating the role of NPY levels interacting with other proinflammatory cytokines are required.