Serum Neuropeptide Y Levels Are Associated with TNF-α Levels and Disease Activity in Rheumatoid Arthritis.
Melissa Ramirez-VillafañaSaldaña-Cruz Ana MiriamJavier Alejandro Aceves-AcevesPerez-Guerrero Edsaul EmilioNicte S Fajardo-RobledoEdy David Rubio ArellanoNava-Valdivia Cesar ArturoMaria O Carrillo-EscalanteSylvia Elena Totsuka-SuttoDavid Cardona MüllerBetsabe Contreras-HaroMario Salazar-PáramoErnesto German Cardona MuñozMiguel HuertaJorge Ivan Gamez-NavaNorma Alejandra Rodriguez-JimenezGonzalez-Lopez LauraPublished in: Journal of immunology research (2020)
Higher NPY levels are an independent marker of disease activity in RA. This study encourages the quantification of NPY levels as a surrogate marker for RA-active. Future studies evaluating the role of NPY levels interacting with other proinflammatory cytokines are required.