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Effectiveness of non-opioid interventions to reduce opioid withdrawal symptoms in patients with chronic pain: a systematic review.

Annely I LangejanLoes de KleijnHanneke J B M Rijkels-OttersStan F J ChudyAlessandro ChiarottoBart W Koes
Published in: Family practice (2021)
Evidence from clinical trials on interventions reducing withdrawal symptoms is scarce. Based on one trial with a small sample size, no firm conclusion can be drawn. Meanwhile, doctors are in dire need for therapeutic options to tackle withdrawal symptoms while tapering patients with prescription opioid dependence. We hope this review draws attention to this unfortunate research gap so that future research can provide doctors with answers.
Keyphrases
  • chronic pain
  • pain management
  • clinical trial
  • physical activity
  • sleep quality
  • randomized controlled trial
  • systematic review
  • phase ii
  • phase iii
  • medical students
  • current status
  • placebo controlled