PET Imaging of TIGIT Expression on Tumor-Infiltrating Lymphocytes.

Travis M ShafferArutselvan NatarajanSanjiv Sam Gambhir

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

This study develops and validates novel TIGIT-specific 64Cu and 89Zr PET probes for quantifying TIGIT expression on TILs for diagnosis of patient selection for anti-TIGIT therapies.

Keyphrases

pet imaging
poor prognosis
positron emission tomography
binding protein
computed tomography
small molecule
long non coding rna
peripheral blood
single molecule
pet ct
photodynamic therapy