Ectopic lipid deposition and insulin resistance in patients with GH disorders before and after treatment.
Mai Christiansen Arlien-SøborgMichael Alle MadsenJakob DalThomas Krusenstjerna-HafstrømSteffen RinggaardNickolaj SkouMorten Lyng HøgildJens Otto Lunde JørgensenPublished in: European journal of endocrinology (2023)
GH status is a significant modulator of body composition and insulin sensitivity.GH excess reduces total fat mass and intrahepatic lipid content together with induction of insulin resistance.The data support the notion that GH-induced insulin resistance is unassociated with hepatic lipid accumulation.
Keyphrases
- body composition
- insulin resistance
- growth hormone
- adipose tissue
- resistance training
- fatty acid
- high fat diet
- metabolic syndrome
- type diabetes
- bone mineral density
- polycystic ovary syndrome
- skeletal muscle
- high fat diet induced
- high glucose
- diabetic rats
- electronic health record
- drug induced
- artificial intelligence
- deep learning
- data analysis