Nuclear export of BATF2 enhances colorectal cancer proliferation through binding to CRM1.
Jie ZhouZengjie LeiJianfang ChenShengbo LiaoYanrong ChenChengxiang LiuShuo HuangLiuli LiYan ZhangPei WangYinghui HuangJianjun LiHoujie LiangPublished in: Clinical and translational medicine (2023)
These findings revealed the biological effects and underlying mechanisms of cytoplasmic localisation of BATF2. Furthermore, suppressing nuclear export of BATF2 via mutating its NES region or inhibiting CRM1 expression may serve as a promising therapeutic strategy against CRC.