Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling.

Michael P MeersDan TenenbaumSteven Henikoff

Published in: Epigenetics & chromatin (2019)

SEACR is a highly selective peak caller that definitively validates the accuracy of CUT&RUN for datasets with known true negatives. Its ease of use and performance in comparison with existing peak calling strategies make it an ideal choice for analyzing CUT&RUN data.

Keyphrases

gene expression
dna damage
electronic health record
transcription factor
genome wide
machine learning
oxidative stress
data analysis
decision making
neural network